LOCAL IgA-MEMORY RESPONSE TO BACTERIAL ANTIGENS
نویسندگان
چکیده
منابع مشابه
Local IgA-memory response to bacterial antigens.
For over 100 years, it has been known that oral immunization can protect against challenge by certain enteropathogenic ba~teria. ' .~ The mechanism of this protection was unclear as most individuals did not demonstrate strong serum agglutinins to the orally administered vaccine. Work by Davies in 1922 provided evidence that agglutinating antibodies in stool specimens from patients with dysenter...
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The character of the antibody response in the rabbit to Salmonella typhimurium somatic (O) antigen was similar to the response to each of several serotypes of Shigella flexneri O antigens, namely a predominance of production of immunoglobulin M (IgM) antibody. Lipopolysaccharide protein (LPSP) and lipopolysaccharide (LPS) fractions of Salmonella O antigen differed significantly in both quantita...
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We compared lymphocyte subsets and cytokine responses to bacteria among term, preterm infants, and adults. Lymphocyte subset percentages in cord blood (22 preterm, 27 term neonates) and peripheral blood from 21 adults and cytokine/chemokine interleukin (IL)-6, IL-8, IL-10, IL-12, interferon gamma (IFN gamma) responses to Escherichia coli, group B Streptococcus (GBS), Staphylococcus epidermidis,...
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Compelling evidence points to a role for IgA receptors in the pathogenesis of IgA nephropathy. The soluble form of the type I IgA receptor (FcalphaRI or CD89) forms complexes with IgA that can be found in patients' serum and that initiate the disease in CD89 transgenic mice. A nonclassic IgA receptor, identified as the transferrin receptor (TfR), is highly expressed in patients' mesangium and c...
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Antibodies to nucleic acid antigens were measured in symptomatic and asymptomatic IgA-deficient individuals, non-IgA-deficient blood donors, and patients with systemic lupus erythematosus (SLE). There was no increase in mean levels of antibodies to nucleic acid antigens (native or denatured DNA, transfer RNA) in the IgA-deficient group, although 4 of 100 IgA-deficient blood donors had persisten...
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ژورنال
عنوان ژورنال: Annals of the New York Academy of Sciences
سال: 1983
ISSN: 0077-8923,1749-6632
DOI: 10.1111/j.1749-6632.1983.tb26912.x